{"product_id":"pathological-and-epidemiological-aspects-of-meningioma-with-special-emphasis-to-sex-hormones","title":"Pathological and epidemiological aspects of meningioma with special emphasis to sex hormones","description":"There is mounting evidence that sex hormones play an important role in development of meningiomas but the tumorigenesis of meningiomas is still largely unknown. The results of previous studies on hormonal treatments and meningioma risk have been equivocal which makes it difficult to draw any definitive conclusions. Carbonic anhydrases (CA) are enzymes that participate in numerous biological processes in humans, including maintenance of the acid-base balance. CA II and IX have recently been shown to be expressed in several cancers but there is little information on their expression in meningiomas. The purpose of this study was to report the expression of sex hormone receptors and carbonic anhydrases II and IX in meningiomas and evaluate the effect of reproductive factors and exogenous sex hormone exposure on meningioma risk in a population-based case-control study and a cohort study.","brand":"Tampere University Press","offers":[{"title":"Default Title","offer_id":32422260408420,"sku":"9789514487637","price":55.95,"currency_code":"EUR","in_stock":true}],"url":"https:\/\/suomalainen-test.myshopify.com\/products\/pathological-and-epidemiological-aspects-of-meningioma-with-special-emphasis-to-sex-hormones","provider":"Suomalainen Test","version":"1.0","type":"link"}